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产品描述:
PDGFR inhibitor 1 is an orally bioavailable switch pocket control inhibitor of wild-type and mutated forms of KIT and PDGFR with potential antineoplastic activity. It also inhibits several other kinases, including VEGFR2, TIE2, PDGFR-beta and CSF1R, thereby further inhibiting tumor cell growth.
化学数据:
分子量Molecular Weight (MW) 489.47 化学式Formula
C26H21F2N5O3
CAS号CAS No. 1225278-16-9 溶解性Solubility (25°C) * 二甲基亚砜DMSO 97 mg/mL (198.17 mM) 水Water Insoluble 乙醇Alcohol 9 mg/mL (18.39 mM)
制备储备液
浓度 溶剂体积(DMSO) 质量 1 mg 5 mg 10 mg 1 mM 2.0430 mL 10.2151 mL 20.4303 mL 5 mM 0.4086 mL 2.0430 mL 4.0861 mL 10 mM 0.2043 mL 1.0215 mL 2.0430 mL 50 mM 0.0409 mL 0.2043 mL 0.4086 mL
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