产品描述：

Tasimelteon is a selective dual melatonin receptor (MT1/MT2) agonist with 2.1-4.4 times greater affinity for the MT2 receptor believed to mediate circadian rhythm phase-shifting (Ki = 0.0692 nM and Ki = 0.17 nM in NIH-3T3 and CHOeK1 cells, respectively), than for the MT1 receptor (Ki = 0.304 nM and Ki = 0.35 nM, respectively).

化学数据：

分子量Molecular Weight (MW)		245.32
化学式Formula		C15H19NO2
CAS号CAS No.		609799-22-6
溶解性Solubility (25°C) *	二甲基亚砜DMSO	49 mg/mL(199.73 mM)
	水Water
	乙醇Alcohol

制备储备液

浓度 溶剂体积(DMSO) 质量	1 mg	5 mg	10 mg
1 mM	4.0763 mL	20.3815 mL	40.7631 mL
5 mM	0.8153 mL	4.0763 mL	8.1526 mL
10 mM	0.4076 mL	2.0382 mL	4.0763 mL
50 mM	0.0815 mL	0.4076 mL	0.8153 mL

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