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产品描述:
Rolapitant is a selective and competitive antagonist of human substance P/NK1 receptors with antiemetic activity. It has a high affinity for the human NK1 receptor of 0.66 nM and high selectivity over the human NK2 and NK3 subtypes of >1000-fold, as well as preferential affinity for human, guinea pig, gerbil and monkey NK1 receptors over rat, mouse and rabbit.
化学数据:
分子量Molecular Weight (MW) 500.48 化学式Formula
C25H26F6N2O2
CAS号CAS No. 552292-08-7 溶解性Solubility (25°C) * 二甲基亚砜DMSO 水Water 乙醇Alcohol
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