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产品描述:
Lurasidone is a second-generation antipsychotic agent that exhibits full antagonism at dopamine D2 and serotonin 5-HT2A receptors with binding affinities Ki = 1 nM and Ki = 0.5 nM, respectively. It also has high affinity for serotonin 5-HT7 receptors (Ki = 0.5 nM), partial agonist activity at 5-HT1A receptors (Ki = 6.4 nM) and lacks affinity for histamine H1 and muscarinic M1 receptors.
化学数据:
分子量Molecular Weight (MW) 492.68 化学式Formula
C28H36N4O2S
CAS号CAS No. 367514-87-2 溶解性Solubility (25°C) * 二甲基亚砜DMSO 7 mg/mL(14.2 mM) 水Water Insoluble 乙醇Alcohol Insoluble
制备储备液
浓度 溶剂体积(DMSO) 质量 1 mg 5 mg 10 mg 1 mM 2.0297 mL 10.1486 mL 20.2972 mL 5 mM 0.4059 mL 2.0297 mL 4.0594 mL 10 mM 0.2030 mL 1.0149 mL 2.0297 mL 50 mM - - -
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