产品描述：

Fruquintinib is a small molecule inhibitor with strong potency and high selectivity against VEGFR family. It inhibits VEGFR 1, 2, 3, with IC50 values of 33 nM, 35 nM and 0.5 nM, respectively and shows only weak inhibition of RET, FGFR-1 and c-kit kinases.

化学数据：

分子量Molecular Weight (MW)		393.39
化学式Formula		C21H19N3O5
CAS号CAS No.		1194506-26-7
溶解性Solubility (25°C) *	二甲基亚砜DMSO	6 mg/mL(15.25 mM)
	水Water	Insoluble
	乙醇Alcohol	Insoluble

制备储备液

浓度 溶剂体积(DMSO) 质量	1 mg	5 mg	10 mg
1 mM	2.5420 mL	12.7100 mL	25.4201 mL
5 mM	0.5084 mL	2.5420 mL	5.0840 mL
10 mM	0.2542 mL	1.2710 mL	2.5420 mL
50 mM	-	-	-

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