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产品描述:
Dasabuvir(ABT-333) is a non-nucleoside inhibitor of NS5B viral RNA-dependent RNA polymerase that inhibits recombinant NS5B polymerases derived from HCV genotype 1a and 1b clinical isolates with IC50 values between 2.2 and 10.7 nM. It is at least 7,000-fold selective for the inhibition of HCV genotype 1 polymerases over human/mammalian polymerases.
化学数据:
分子量Molecular Weight (MW) 493.57 化学式Formula
C26H27N3O5S
CAS号CAS No. 1132935-63-7 溶解性Solubility (25°C) * 二甲基亚砜DMSO 98 mg/mL(198.55 mM) 水Water Insoluble 乙醇Alcohol Insoluble
制备储备液
浓度 溶剂体积(DMSO) 质量 1 mg 5 mg 10 mg 1 mM 2.0261 mL 10.1303 mL 20.2606 mL 5 mM 0.4052 mL 2.0261 mL 4.0521 mL 10 mM 0.2026 mL 1.0130 mL 2.0261 mL 50 mM 0.0405 mL 0.2026 mL 0.4052 mL
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