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产品描述:
Daminozide, a plant growth regulator, selectively inhibits the KDM2/7 JmjC subfamily with IC50 of 1.5±0.7 μM for KDM2A. It is at least 100-fold selective as an inhibitor of the KDM2/7 subfamily over the other demethylase subfamily members tested, with IC50s of 2 μM or less against KDM2A, PHF8, and KIAA1718 and IC50s of 127 μM for KDM3A or greater (mM range) against other demethylases.
化学数据:
分子量Molecular Weight (MW) 160.17 化学式Formula
C6H12N2O3
CAS号CAS No. 1596-84-5 溶解性Solubility (25°C) * 二甲基亚砜DMSO 32 mg/mL(199.78 mM) 水Water 乙醇Alcohol
制备储备液
浓度 溶剂体积(DMSO) 质量 1 mg 5 mg 10 mg 1 mM 6.2434 mL 31.2168 mL 62.4337 mL 5 mM 1.2487 mL 6.2434 mL 12.4867 mL 10 mM 0.6243 mL 3.1217 mL 6.2434 mL 50 mM 0.1249 mL 0.6243 mL 1.2487 mL
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