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产品描述:
Bedaquiline, a diarylquinoline, binds to subunit c of mycobacterial ATP synthase and inhibits its activity. It is highly selective for mycobacterial ATP synthase enzyme compared to homologous eukaryotic enzyme (Selectivity Index >20 000).
化学数据:
分子量Molecular Weight (MW) 555.50 化学式Formula
C32H31BrN2O2
CAS号CAS No. 843663-66-1 溶解性Solubility (25°C) * 二甲基亚砜DMSO 12 mg/mL(21.6 mM) 水Water Insoluble 乙醇Alcohol 3 mg/mL(5.4 mM)
制备储备液
浓度 溶剂体积(DMSO) 质量 1 mg 5 mg 10 mg 1 mM 1.8002 mL 9.0009 mL 18.0018 mL 5 mM 0.3600 mL 1.8002 mL 3.6004 mL 10 mM 0.1800 mL 0.9001 mL 1.8002 mL 50 mM - - -
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